Attempting to solve the Storyville district murders in 1910 New Orleans, Dr. Eric Trevor discovers that Detective Donahue is much more resourceful than he thought as he is invited to participate in Donahue's "private" investigation since officially things have to be kept quiet so as not to disrupt the thriving 'legal' economic base of Storyville. New to the city, Trevor finds out about the past of Storyville while at the same time attending to his Saint James Infirmary patients, including a 15-year-old boy who murdered his two friends for no apparent reason. Trevor explains to the investigative police team about the ideas behind Jack the Ripper and how the cases, then and now might be eerily similar.
