This Yu-Gi-Oh spinoff explores more serious themes. The story takes place in a dystopian future where Domino City has been divided into Neo Domino and the Satellite sector after a tragic incident. Satellite residents are looked down upon.
A mysterious new threat arrives on the scene in New Domino City, forcing Yusei to take to the streets and track down a rogue Turbo Duelist known as The Ghost.
With his life points on the line, Yusei must figure out a way to take down Ghost's Meklord Emperor Wisel before Wisel's special ability throws his game and his runner into a tailspin.
When Vice Chancellor Rudolph Heitmann threatens to expel all the members of Leo and Luna's class from Duel Academy, Yusei attempts to teach the teacher a valuable lesson by challenging the Vice Chancellor to a duel to keep his friends in school.
When Crow is asked to convince an old friend of Martha's to move into her retirement home, Crow decides to tackle the task by challenging the old man to a trash-talking junkyard duel.
When a loan shark starts sinking his teeth into New Domino City, Jack decides to reel in this money-grubbing menace for good by putting his most prized possessions on the line in a duel.
When Leo and Luna decide to go exploring a nearby forest rumored to be haunted by wicked spirits, they soon discover that the rumors are all too real when a mysterious boy traps Luna in his house and challenges Leo to a duel.
As the battle between Yusei and Sherry races on, Sherry reveals some shocking secrets about the upcoming World Racing Grand Prix. Meanwhile, Akiza begins to gain a new understanding and appreciation for Turbo Dueling while riding shotgun to Yusei.
Before heading out to the event of the year - The World Racing Grand Prix Gala - Yusei challenges Jack to a Turbo Duel in the hopes of finding a new dueling strategy that doesn't involve the use of Synchro Monsters.